Generic Name: Rasagiline (ra SA ji leen)
Brand Name: Azilect

Medically reviewed by Drugs.com. Last updated on Aug 19, 2020.

Uses of Rasagiline:

• It is used to treat Parkinson's disease.

What do I need to tell my doctor BEFORE I take Rasagiline?

• If you have an allergy to rasagiline or any other part of rasagiline.
• If you are allergic to rasagiline; any part of rasagiline; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you have liver disease.
• If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with rasagiline, like certain drugs that are used for cough or cold, depression or other mood problems, or pain. There are many drugs that must not be taken with rasagiline.
• If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline in the last 14 days. Taking rasagiline within 14 days of those drugs can cause very bad high blood pressure.
• If you have taken fluoxetine within the last 5 weeks. Do not start rasagiline if you have taken fluoxetine within the last 5 weeks.

This is not a list of all drugs or health problems that interact with rasagiline.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take rasagiline with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

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What are some things I need to know or do while I take Rasagiline?

• Tell all of your health care providers that you take rasagiline. This includes your doctors, nurses, pharmacists, and dentists.
• Avoid driving and doing other tasks or actions that call for you to be alert until you see how rasagiline affects you.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
• Do not stop taking rasagiline all of a sudden without calling your doctor. You may have a greater risk of side effects. If you need to stop rasagiline, you will want to slowly stop it as ordered by your doctor.
• Some foods and drinks, like cheese and red wine, may cause sudden, severe high blood pressure when you are taking rasagiline. This effect can be deadly. Talk with your doctor about your risk for this effect. Get a list of foods and drinks to avoid. Avoid these foods and drinks for as long as your doctor has told you after rasagiline is stopped.
• Some people have fallen asleep during activities like driving, eating, or talking. Some people did not feel sleepy and felt alert right before falling asleep. This has happened up to 1 year after rasagiline was started. If you fall asleep during activities, do not drive or do other tasks or actions that call for you to be alert while you take rasagiline. Call your doctor right away if this happens or you feel very sleepy.
• High or low blood pressure may happen with rasagiline. Have your blood pressure checked as you have been told by your doctor.
• If you are taking rasagiline and have high blood pressure, talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.
• The chance of a type of skin cancer called melanoma may be raised in people with Parkinson's disease. It is not known if rasagiline may also raise the chance. Have skin exams while you take rasagiline. Talk with your doctor.
• Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
• Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using rasagiline while you are pregnant.
• Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Rasagiline) best taken?

Use rasagiline as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take with or without food.
• Keep taking rasagiline as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

• Skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
• Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking.
• Shakiness, trouble moving around, or stiffness.
• Strong urges that are hard to control (such as eating, gambling, sex, or spending money).
• A skin lump or growth.
• Change in color or size of a mole.
• Hallucinations (seeing or hearing things that are not there).
• Change in the way you act.
• Mood changes.
• Shortness of breath.
• A burning, numbness, or tingling feeling that is not normal.
• Swelling in the arms or legs.
• A severe and sometimes deadly problem called serotonin syndrome may happen if you take rasagiline with certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or severe headache.

What are some other side effects of Rasagiline?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Flu-like signs.
• Headache.
• Upset stomach or throwing up.
• Constipation.
• Diarrhea.
• Dizziness.
• Feeling sleepy.
• Dry mouth.
• Not hungry.
• Belly pain.
• Weight loss.
• Strange or odd dreams.
• Joint pain.
• Bruising.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Rasagiline?

• Store at room temperature.
• Store in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about rasagiline, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about rasagiline

• During Pregnancy or Breastfeeding

Consumer resources

Other brands:Azilect

Professional resources

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